GLP Test Article Handling and Storage Audit Checklist

A comprehensive checklist for auditing the handling, storage, and management of test articles in GLP-regulated pharmaceutical research, ensuring compliance and maintaining the integrity of research materials.

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About This Checklist

Proper handling and storage of test articles is critical for maintaining the integrity of pharmaceutical research conducted under Good Laboratory Practice (GLP) standards. This GLP Test Article Handling and Storage Audit Checklist is designed to help quality assurance personnel, study directors, and laboratory managers evaluate and improve processes related to the receipt, storage, handling, and disposal of test articles. By implementing this checklist, pharmaceutical organizations can ensure compliance with GLP regulations, maintain the quality and stability of test articles, and enhance the overall reliability of their research studies.

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Industry

Healthcare

Standard

GLP - Good Laboratory Practice

Workspaces

Pharmaceutical Research Facilities

Occupations

Quality Assurance Specialist
Study Director
Laboratory Manager
Test Article Coordinator
GLP Compliance Officer
1
Is there a documented procedure for the traceability of test articles?

Select compliance status.

This ensures that all test articles can be tracked throughout their lifecycle, which is crucial for compliance with GLP regulations.
2
Are integrity checks performed on samples before testing?

Indicate whether integrity checks are performed.

Regular integrity checks are vital to ensure the quality and reliability of test results.
3
What is the current storage temperature for test articles?

Enter the storage temperature in degrees Celsius.

Maintaining appropriate storage conditions is crucial for preserving the integrity of pharmaceutical materials.
Min15
Target20
Max25
4
Are all test articles stored in compliance with GLP regulations?

Select compliance status.

Compliance with GLP storage regulations is necessary for the validity of research and test results.
5
Are there established handling protocols for all test substances?

Select handling protocol status.

Proper handling protocols ensure safety and prevent contamination during testing.
6
What is the procedure for reporting incidents involving test substances?

Describe the incident reporting procedure.

Having a clear incident reporting procedure is essential for addressing and mitigating risks associated with test substances.
7
Provide details on training records for personnel handling test substances.

Enter details on training records.

Training records demonstrate that personnel are knowledgeable about handling test substances, which is critical for compliance.
8
When was the last review of the handling procedures conducted?

Select the date of the last review.

Regular reviews of handling procedures help ensure ongoing compliance and safety.
9
Are there documented quality control procedures for test articles?

Select the status of quality control procedures.

Documented procedures ensure consistency and adherence to GLP standards in quality control.
10
What is the sample size used for quality control testing?

Enter the number of samples used for QC testing.

The sample size must be adequate to ensure the reliability of quality control results.
Min5
Target10
Max50
11
Is quality control testing conducted on a regular basis?

Indicate whether QC testing is performed regularly.

Regular QC testing is essential for maintaining the integrity and quality of test articles.
12
Document any findings or deviations from the quality control procedures.

Enter details of quality control findings.

Documenting findings is critical for continuous improvement and compliance with GLP regulations.
13
Is there an inventory tracking system in place for test articles?

Select the status of the inventory tracking system.

An effective inventory tracking system ensures that all test articles are accounted for and facilitates compliance with GLP standards.
14
What is the maximum inventory level for test articles?

Enter the maximum inventory level.

Setting a maximum inventory level helps prevent overstocking and ensures efficient resource management.
Min50
Target100
Max200
15
Are regular audits conducted on the test article inventory?

Indicate whether inventory audits are performed regularly.

Regular audits help ensure the accuracy of inventory records and compliance with GLP regulations.
16
What is the procedure for handling inventory discrepancies?

Describe the procedure for handling inventory discrepancies.

A clear procedure for addressing discrepancies is essential for maintaining inventory integrity and compliance.
17
Are there documented disposal protocols for test articles?

Select the status of disposal protocols.

Documented protocols ensure safe and compliant disposal of test articles in accordance with GLP regulations.
18
When was the last review of disposal procedures conducted?

Select the date of the last review.

Regular reviews ensure that disposal procedures remain effective and compliant with regulations.
19
Have personnel received training on disposal procedures for test articles?

Indicate whether personnel have been trained.

Training is essential to ensure that all personnel understand and follow proper disposal procedures.
20
Document any incidents related to the disposal of test articles.

Enter details of disposal incident reports.

Keeping records of incidents helps improve disposal practices and ensures compliance with GLP regulations.

FAQs

The checklist covers areas such as receipt and logging procedures, storage conditions, labeling and identification, handling and dispensing practices, expiration date monitoring, and disposal protocols for test articles.

Audits should be conducted at least semi-annually, with more frequent checks recommended for high-turnover test articles or when there are significant changes in storage facilities or handling procedures.

The audit should be conducted by quality assurance personnel in collaboration with study directors and laboratory managers responsible for test article management.

By ensuring proper handling and storage of test articles, this checklist helps maintain the quality and stability of materials used in studies, thereby supporting the validity and reproducibility of research results.

Yes, while maintaining core GLP principles, the checklist can be tailored to address specific requirements for different types of test articles, such as small molecules, biologics, or medical devices.

Benefits of GLP Test Article Handling and Storage Audit Checklist

Ensures compliance with GLP regulations for test article management

Minimizes risks of test article contamination, degradation, or mix-ups

Improves traceability and documentation of test article lifecycle

Enhances the reliability and reproducibility of research studies

Facilitates efficient inventory management of test articles